In our latest question and also answer, the pharmacist discusses whether or not NyQuil have the right to be taken v Tessalon (benzonatate).

You are watching: Can i take benzonatate and nyquil together


Rick asked

I took a prescription sneeze suppressant my doctor prescribed, benzonatate, 200mg around 4-1/2 hrs ago. Ns would prefer to currently take 30ml the NyQuil significant cold & flu for the remainder of the symptoms. Will there be any type of adverse reactions?


There is no interaction in between benzonatate and NyQuil. They room generally considered to be safe to take it together.

However, NyQuil will cause sedation around 30 come 60 minute after taking by mouth and benzonatate may reason mild sedation in part individuals. Therefore, there is a opportunity of additive sedative results with the two medications.

Benzonatate Information

Benzonatate (brand surname Tessalon) is a non-narcotic medication, most typically used for cough symptoms connected with colds and also acute respiratory infections. At common dosages, benzonatate is not associated with respiratory tract depression or significant CNS (central nervous system) depressionand is because of this considered for sure to take it with many other medications.

Benzonatate works by anesthetizing the stretch receptor in the alveoli the the lungs and airways. This reduce the emotion of needing to cough.

While benzonatate is typically really well tolerated, that can reason mild sedation. When an unified with other medicines that cause sedation, such as NyQuil, the sedative results can be enhanced and you should not operate heavy machinery or partake in activities that need strict attention.

NyQuil Information

NyQuil is a combination cough/cold medicine that consists of the adhering to ingredients:

Acetaminophen (analgesic)Dextromethorphan (cough suppressant)Doxylamine (sedating antihistamine)

While NyQuil go contain a cough suppressant (dextromethorphan), that is not thought to communicate with benzonatate.

Doxylamine, the sedating antihistamine in NyQuil, might potentially cause additive effects of sedation with offered with benzonatate. Doxylamine starts to job-related in around 30 minutes but peak concentration in the blood occur almost 2 come 3 hrs after acquisition by mouth. This way that while you will feel the results of doxylamine reasonably quickly, it deserve to take a few hours because that the medicine to reach max effect.

See more: How Does The Number Of Electron Pairs Around A Central Atom Determine Its Shape

Taking Benzonatate with NyQuil

As mentioned above, there is no interaction in between benzonatate and NyQuil. However, NyQuil will almost assuredly reason sedition and benzonatate may have actually mild sedative impacts as well. Therefore, although over there is no drug-drug interaction in between the two, caution is advised once using the mix due come the additive sedative effects.