Medically reviewed by Alan Carter, Pharm.D. — written by Jill Seladi-Schulman, Ph.D. On December 19, 2018

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Acetaminophen (Tylenol) and also ibuprofen (Advil) room both over-the-counter (OTC) medications that can be offered to relieve pain.

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These drugs are two different varieties of pain relievers. Acetaminophen, sometimes listed as APAP, is its very own type, while ibuprofen is a nonsteroid anti-inflammatory medicine (NSAID).

Generally, it’s for sure to take it acetaminophen and ibuprofen together, but you’ll want to pay close attention to how much you take of every medication.

The vital to safely acquisition acetaminophen and also ibuprofen is knowing just how much you’re taking at a time and how often.

Acetaminophen dosage

The maximum for sure dosage of paracetamol for anyone over the age of 12 is 4,000 milligrams (mg) per day. Yet even this amount can harm some people’s livers, so aim because that no an ext than 3,000 mg every day.

For children under the age of 12, it’s finest to check with their healthcare provider to determine the safest sheep for your body weight.

Keep in mental that plenty of OTC drugs contain paracetamol in a selection of doses, commonly 325 mg, 500 mg, or 650 mg.

Some examples of brand-name OTC medications that might contain acetaminophen include:


Remember: once looking at labels, girlfriend might likewise see acetaminophen detailed as APAP.

Ibuprofen dosage

Avoid taking an ext that 1,200 mg of ibufrofen in a single day. OTC ibuprofen is often found in 200 mg pills. This converts to six pills a day. Still, you should always verify exactly how much is in each pill.

Again, for children, it’s finest to ask their healthcare provider about the safest sheep for their weight.

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If you have actually prescription-strength ibuprofen, talk to your prescriber prior to mixing the with any type of other medications, consisting of acetaminophen.


The recommended borders for adults and also children end 12 are:

3,000 mg per day that acetaminophen1,200 mg every day the ibuprofen

For kids under the age of 12, call their health care provider or refer to the product brand for dosage guidelines.

You have the right to take ibuprofen and acetaminophen at the same time. Just make sure to not take an ext than the recommended dose.

Some human being experience some stomach or abdominal pain as soon as taking the two drugs together. In this case, it’s much better to alternative when you take it each medication.

For example, you might take ibuprofen first, complied with by acetaminophen four hours later, and also then repeat this process as needed.

You could additionally alternate days. Because that example, if you take ibuprofen top top Monday, take paracetamol on Tuesday and so on.