Main difference – Binary Fission vs Mitosis

Binary fission and mitosis are two mechanisms offered in the asexual reproduction that organisms. A solitary organism is divided into 2 daughter organisms during the binary fission. Binary fission is the asexual reproduction system in prokaryotes. Mitosis is the vegetative cell department in eukaryotes. Asexual reproduction or the vegetative cell division is offered for the growth, development, and also replacement of cell in eukaryotes. The main difference between binary fission and mitosis is the binary fission walk not kind a spindle apparatus whereas mitosis takes place through the spindle apparatus.

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1. What is Binary Fission – Mechanism, Types, Speed 2. What is Mitosis – Mechanism, Phases 3. What is the difference between Binary Fission and Mitosis


What is Binary Fission?

The division of a single organism into two daughter organisms is well-known as binary fission. Bacteria and also archaea favor prokaryotes typically exhibit binary fission together the cell division mechanism in their asexual reproduction. Part eukaryotic organelles prefer mitochondria additionally exhibit binary fission in order to rise their number inside the cell. Prokaryotes save on computer a single, circular chromosome in the genome. This DNA molecule is replicated prior to the cell division. While the parental cell traction apart, replicated chromosomes space separated. Resultant two cells room genetically identical and also have a potential to prosper its original size in the species.


DNA replication is the first event in the process of binary fission. The solitary circular chromosome in the vegetative cell is strictly coiled. It becomes uncoiled and also then is replicated. Replicated 2 chromosomes relocate to opposing poles by an energy-dependent process. Climate the cell boosts its length. Every the components like ribosomes and plasmids that the prokaryotic cell double their number. The equatorial key constricts in bespeak to different the plasma membrane. A brand-new cell wall forms between the separated cells. The division of the cytoplasm is recognized as cytokinesis. The 2 newly created cells contain approximately equal variety of ribosomes, plasmids and also other components. The volume of the cytoplasm is additionally approximately equal.


Figure 1: Binary Fission

Types that Binary Fission

Four varieties of binary fission have the right to be identified.

Irregular binary fission – cytokinesis takes ar in the perpendicular aircraft to the plane which karyokinesis has actually taken place. It wake up in amoeba.

Longitudinal binary fission – cytokinesis occurs along the longitudinal axis. This occurs in flagellates and Euglena.

Transverse binary fission – cytokinesis occurs follow me the transverse axis. It wake up in paramecium choose protozoans.

Oblique binary fission – slope cytokinesis occurs as in ceratium.


Figure 2: Binary fission in Salmonella typhimurium bacterium


Binary fission is considered as a fast process. Typically, one E. Coli cell at 37 °C divides every 20 minutes. The whole bacterial society undergoes binary fission; therefore the time taken by one bike is referred to as the copy time. Some strains favor Mycobacterium tuberculosis have slow copy time contrasted to E. Coli.

What is Mitosis

The vegetative cell division in eukaryotes is recognized as mitosis. Replicated genome is divided, developing two daughter nuclei followed by the cytoplasmic division which may ultimately develop two cells from a single parent cell. The 2 cells space identical, bearing approximately equal variety of organelles and also cytoplasm. The mitotic phase is referred to as the M phase of the cabinet cycle. Various species of mitosis deserve to be identified amongst organisms. Throughout the “open” mitosis in animals, nuclear envelope is broken down in order to different the chromosomes. But in fungi, chromosomes separate in the undamaged nucleus; this is called as “closed” mitosis.

Eukaryotes use mitosis in your asexual reproduction, growth and also development, instead of of body cells and regeneration of body parts. 


Mitotic division can be split into four major stages: prophase, metaphase, anaphase and the telophase. The chromosomes in the cell space replicated in ~ the S step of the interphase, before entering the M phase. They are additionally condensed and also attached to the spindle fibers. Proteins forced for the cell division are synthesized during the interphase. Cellular contents including oribel are also doubled throughout the interphase.


During pre-prophase, the cell nucleus of the very vacuolated tree migrates to the center of the cell. Prophase is the first stage of the nuclear department in mitosis. At at an early stage prophase, the core source disappears. The chromosomes space tightly coiled and the development of the mitotic spindle is initiated at the prophase. Chromosomes, containing 2 sister chromatids which room joined together at the centromere can be visualized as thin, long, thread-like frameworks under the light microscope. A pair of centrosomes shows up close to the nucleus i m sorry is surrounded by protein fibers, developing the microtubule spindle apparatus. Plants perform not own a centrosome, i beg your pardon is the coordinating center of microtubules. Thus, the formation of spindle apparatus is not important for the cell division in plants. 


Nuclear envelope disappears throughout the prometaphase of open up mitosis. The kinetochore microtubules are attached to the kinetochores in chromosomal centromeres. The growth of the mitotic spindle takes location by connecting polar microtubules together. Two centrosomes traction chromosomes towards the opposite poles by contracting the microtubules. Due to the tension, chromosomes room aligned in the equatorial plate of the cell at the metaphase. Metaphase checkpoint ensures the equal distribution of the chromosomes at the equatorial plate.


During anaphase, sister chromatids room separated by the pulling tension created by the centrosomes, creating two daughter chromosomes. This daughter chromosomes space pulled to the the contrary poles by additional contracting microtubules. 


The contract microtubules room loosened, lengthening the cell. A brand-new nuclear envelope is formed, enclosing two chromosome sets at the opposite poles, reappearing two nuclei. 


Figure 3: Phases of Mitosis


The karyokinesis wake up in the M phase, followed by cytokinesis, the department of the cytoplasm, a procedure which is separated native the M phase. Plant cytokinesis is different from animal cytokinesis because of the presence of a cabinet wall. In animal cells, a cleavage furrow is formed in order to pinch turn off the cytoplasm with the help of contractile ring, arisen at metaphase that karyokinesis. In plants, a cell plate is created in the middle of the parent cell i beg your pardon matures to fuse through the existing cabinet wall. Both animal and plant cell cytokinesis are thrust by the vesicles coming from the Golgi apparatus. In many organisms, karyokinesis and also cytokinesis take ar separately.

Difference in between Binary Fission and Mitosis


Binary Fission: Binary fission is the division of a single organism into two daughter organisms.

Mitosis: Mitosis is the vegetative cell department in eukaryotes. 

Type that Organism

Binary Fission: Binary fission mostly takes place in prokaryotes.

Mitosis: Mitosis takes location in eukaryotes.


Binary Fission: Binary fission does not take location in organisms who have a nucleus.

Mitosis: Mitosis takes ar in organisms that possess a nucleus.

Formation of the Spindle Apparatus

Binary Fission: A spindle apparatus is not formed throughout binary fission.

Mitosis: Eukaryotes own a spindle apparatus throughout mitosis.

Doubling that Organelles

Binary Fission: Prokaryotes execute not have actually organelles. However, ribosomes and also other cellular contents are doubled before binary fission.

Mitosis: Organelles room doubled in ~ the interphase in order come separate into two cells.


Binary Fission: Asexual reproduction in prokaryotes is the duty of the binary fission.

Mitosis: Eukaryotes use mitosis for asexual reproduction, growth and development, replacement of human body cells and also regeneration human body parts.


Binary Fission: DNA is directly attached come the cabinet membrane throughout the binary fission.

Mitosis: DNA is attached come the spindle apparatus throughout the mitotic division.


Binary Fission: Binary fission is a less reliable process, resulting in increased variety of chromosomes in a cell.

Mitosis: Mitosis is corrected with metaphase checkpoint in stimulate to preserve a uniform chromosome number.


Binary Fission: Binary fission is a simple process.

Mitosis: Mitosis is comparatively facility than the binary fission.

Time Taken

Binary Fission: Binary fission is a quick process.

Mitosis: Mitosis takes some time due to its complexity.


Binary Fission: Binary fission takes ar in bacteria and eukaryotes prefer ameba, Hydra, and planaria.

Mitosis: Mitosis takes ar in all pets including humans, every plants, and fungi.


Binary fission and also mitosis are two varieties of asexual reproduction mechanisms uncovered in prokaryotes and eukaryotes, respectively. Mitosis takes location through number of phases, separating the nucleus of eukaryotic bio cells. It has a greater reliability due to the fact that corrections occur throughout metaphase checkpoint in stimulate to maintain a resolved chromosome number in the progeny. Hence, that is a time taking and more complicated process contrasted to binary fission. Therefore, the main difference between binary fission and also mitosis is their complexity.

See more: How Thick Is The Human Skull ? Human Skull: Anatomy And Physiology

Reference:1. “Fission (Biology)”. N.p., 2017. Web. 8 Mar. 2017. 2.”Mitosis”. N.p., 2017. Web. 8 Mar. 2017.

Image Courtesy:1. “Binary Fission 2” through Ecoddington14 – (CC BY-SA 3.0) via Commons Wikimedia2. “Under a an extremely high magnification of 15000X, this colorized scanning electron micrograph (SEM) revealed the existence of a single Gram-ne” by CDC/ Bette Jensen via public Domain Files 3. “Mitosis Stages” by Ali Zifan – very own work; Used info from: Campbell biological (10th Edition) by: woman B. Reece & Steven A. Wasserman.and (CC BY-SA 4.0) via Commons Wikimedia