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You are watching: Is ch3o- a strong base

I think that strong base + alcohol reasons elimination. Destroyer #147 in orgo has actually primary halide + CH3O- + alcohol and also it walk substitution reaction. I believe this is wilhelm ether synthetic which is SN2. Destroyer #31 in orgo has tertiary halide + CH3OH + alcohol and also it go substitution reaction. ~ seeing problems like this, i think CH3O- is exact same as CH3OH and also both that them could be weak base due to the fact that they reason substitution instead of elimination but Destroyer #143 mirrors that C2H5O- with alcohol causes elimination reaction. go this typical CH3O- is weak base yet C2H5O- is a strong base?
Williamson Ether synthetic happens when an organometallic link (CH3ONa) reacts v a primary,sometimes secondary, halide through SN2. This is a special case, and also you have
to have an organometal and alkyl halide because that it come happen. Tertiary halides experience SN1 substitution as the significant product, with some elimination as minor product under the best conditions. -OH is no a an excellent leaving group. The conjugate basic of weak mountain are strong bases. MeO- and also EtO- are solid bases. MeOH and also EtOH are weak nucleophiles.
dentrilla
Yah Destroyer #147 is especially wierd due to the fact that it undergoes SN2 when in a protic solvent. It states that main halide will undergo ether synthesis as soon as you include CH3O- and also CH3OH (protic solvent) by one SN2 mechanism....
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